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Search Result

Search Results for " apoptosis-specific protein "

Targets

Apoptosis NADPH-oxidase

15

Compounds

4

Natural Products

35

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T29097 VAS 3947 VA-S3947,VA S3947,VAS3947 Apoptosis , NADPH-oxidase
VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to protein aggregation and misfolding, independent of anti-NOX act...
T6248 XL888 HSP
XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis....
T11600 IBR2 Isoquinoline DNA/RNA Synthesis
IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RA...
TQ0081 JPH203 KYT-0353 Others
JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-infl...
T16087 Quiflapon MK-591 Apoptosis , FLAP
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr...
T22070 DBIBB LPA Receptor
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma ra...
T61106 GRP78-IN-1
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ...
T75931 Difopein TFA
Difopein (TFA), a specific competitive inhibitor of the 14-3-3 protein (a universally conserved regulatory molecule in eukaryotes), impedes 14-3-3's binding capability with its target proteins and obstructs 14-3-3/Ligand...
TP1551 Difopein TFA (396834-58-5 free base) Difopein TFA
Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interaction...
T62977 MA242 free base
MA242 free base is a specific dual inhibitor of MDM2 and NFAT1 that induces apoptosis in pancreatic cancer cell lines. MA242 free base binds directly to MDM2 and NFAT1 with high affinity, induces MDM2 and NFAT1 protein d...
T73257 USP7-IN-9
USP7-IN-9, a potent inhibitor of ubiquitin-specific protease 7 (USP7) with an IC50 of 40.8 nM, effectively induces apoptosis and arrests cell progression at the G0/G1 and S phases in RS4;11 cells. It decreases the protei...
T78296 IMAB027 ASP1650
IMAB027 (ASP1650) is a specific monoclonal antibody targeting CLDN6 (Claudin 6), a membrane protein of tight junctions aberrantly overexpressed in multiple human cancers, notably in ovarian cancers. This compound exhibit...
T78055 MYC-RIBOTAC c-Myc
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. Th...
T35578 Phosphatidylserines (sodium salt) Phosphatidylserines (sodium salt),L-α-Phosphatidylserine
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T36894 5-Bromouridine
5-Bromouridine is a brominated analog of the nucleoside uridine .1It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine .25-Bromouridine decreases the viability of HL-60 and MO...
Cat No. Product Name Synonyms Targets
T11665 Ionomycin calcium SQ23377 calcium Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC
lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly spec...
T1719 Bufalin ATPase
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...
T16381 Okadaic acid Others
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted fr...
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...

Natural Products

Ionomycin calcium
T11665
Synonym: SQ23377 calcium
Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC
Bufalin
T1719
Synonym:
Target: ATPase
Okadaic acid
T16381
Synonym:
Target: Others
Phosphatidylserines (bovine)
T35577
Synonym:
Target:

Recombinant Proteins

Species：
Human (28)
Mouse (3)
Human & Mouse (2)
Cynomolgus (1)
Expression System：
HEK293 Cells (17)
E. coli (14)
Baculovirus Insect Cells (3)
Tag：
His (7)
C-His-Avi (6)
C-6xHis (4)
Tag Free (3)
C-hFc (2)
GST (2)
N-6xHis (2)
N-His (2)
Avi (1)
C-Avi-6xHis (1)
Cat No. Product Name Species Expression System
TMPJ-01329 ATG5 Protein, Human, Recombinant Human E. coli
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic ce...
TMPY-04830 GAS6 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-05058 TMX1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in t...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPK-01549 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting d...
TMPK-01548 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01554 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPJ-01059 CRADD Protein, Human, Recombinant Human E. coli
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD do...
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His) Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPY-01176 CIAP1 Protein, Human, Recombinant (Avi) Human E. coli
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
TMPY-01841 Serpin I2 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-00365 GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated Human HEK293 Cells
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signa...
TMPH-02222 TEAD1 Protein, Human, Recombinant (His) Human E. coli
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPJ-01074 PKCE Protein, Human, Recombinant (His) Human E. coli
Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these doma...
TMPY-05095 RAF1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct...
TMPY-02640 FAM3B Protein, Human, Recombinant (hFc) Human HEK293 Cells
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b...
TMPJ-00366 GAS6 Protein, Human, Recombinant (hFc) Human HEK293 Cells
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds...
TMPY-04999 GAS6 Protein, Human, Recombinant (His)
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds...
TMPJ-01097 ZBTB17 Protein, Human, Recombinant (His) Human E. coli
Zinc Finger and BTB Domain-Containing Protein 17 (ZBTB17) belongs to the Kruppel C2H2-type zinc finger protein family. ZBTB17 may function as a housekeeping DNA-binding protein that regulates the expression of specific g...
TMPY-03498 ING4 Protein, Human, Recombinant (His) Human E. coli
ING4 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. ING4 contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His) Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit va...
TMPJ-01081 Dtk Protein, Human, Recombinant (His) Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs an...
TMPY-01775 AIM2 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPY-01577 ORP150 Protein, Human, Recombinant (His) Human HEK293 Cells
Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four differen...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His) Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in...
TMPY-01589 Serpin B10 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-02213 RAIDD Protein, Human, Recombinant (His) Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu...
TMPY-02228 P53 Protein, Cynomolgus, Recombinant Cynomolgus E. coli
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and...
TMPY-02981 ING5 Protein, Human, Recombinant (GST) Human E. coli
ING5 belongs to the ING family. It contains 1 PHD-type zinc finger and is a component of the HBO1 complex. HBO1 complex has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is re...
TMPY-02300 BIN1 Protein, Human, Recombinant (His) Human E. coli
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
ATG5 Protein, Human, Recombinant
TMPJ-01329
Species: Human
Expression System: E. coli
GAS6 Protein, Mouse, Recombinant (His)
TMPY-04830
Species: Mouse
Expression System: HEK293 Cells
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
TMX1 Protein, Human, Recombinant (mFc)
TMPY-05058
Species: Human
Expression System: HEK293 Cells
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
TMPJ-00770
Species: Mouse
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01549
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
TMPK-00276
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01548
Species: Human
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01554
Species: Human
Expression System: HEK293 Cells
CRADD Protein, Human, Recombinant
TMPJ-01059
Species: Human
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TMPK-00277
Species: Human
Expression System: HEK293 Cells
Caspase-10 Protein, Human, Recombinant (His)
TMPJ-01256
Species: Human
Expression System: E. coli
cIAP1 Protein, Human, Recombinant (Avi)
TMPY-01176
Species: Human
Expression System: E. coli
Serpin I2 Protein, Human, Recombinant (His)
TMPY-01841
Species: Human
Expression System: HEK293 Cells
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00365
Species: Human
Expression System: HEK293 Cells
TEAD1 Protein, Human, Recombinant (His)
TMPH-02222
Species: Human
Expression System: E. coli
PKCE Protein, Human, Recombinant (His)
TMPJ-01074
Species: Human
Expression System: E. coli
RAF1 Protein, Human, Recombinant (His & GST)
TMPY-05095
Species: Human
Expression System: Baculovirus Insect Cells
FAM3B Protein, Human, Recombinant (hFc)
TMPY-02640
Species: Human
Expression System: HEK293 Cells
GAS6 Protein, Human, Recombinant (hFc)
TMPJ-00366
Species: Human
Expression System: HEK293 Cells
GAS6 Protein, Human, Recombinant (His)
TMPY-04999
Species:
Expression System:
ZBTB17 Protein, Human, Recombinant (His)
TMPJ-01097
Species: Human
Expression System: E. coli
ING4 Protein, Human, Recombinant (His)
TMPY-03498
Species: Human
Expression System: E. coli
OLFM4 Protein, Human, Recombinant (His)
TMPY-01416
Species: Human
Expression System: HEK293 Cells
Dtk Protein, Human, Recombinant (His)
TMPJ-01081
Species: Human
Expression System: HEK293 Cells
AIM2 Protein, Human, Recombinant (GST)
TMPY-01775
Species: Human
Expression System: Baculovirus Insect Cells
ORP150 Protein, Human, Recombinant (His)
TMPY-01577
Species: Human
Expression System: HEK293 Cells
BCL2A1 Protein, Human, Recombinant (His)
TMPY-04936
Species: Human
Expression System: E. coli
Serpin B10 Protein, Mouse, Recombinant (His)
TMPY-01589
Species: Mouse
Expression System: Baculovirus Insect Cells
RAIDD Protein, Human, Recombinant (His)
TMPY-02213
Species: Human
Expression System: E. coli
p53 Protein, Cynomolgus, Recombinant
TMPY-02228
Species: Cynomolgus
Expression System: E. coli
ING5 Protein, Human, Recombinant (GST)
TMPY-02981
Species: Human
Expression System: E. coli
BIN1 Protein, Human, Recombinant (His)
TMPY-02300
Species: Human
Expression System: E. coli
Cat No. Product Name
L1610 FDA-Approved Kinase Inhibitor Library

263 compounds
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L3800 NF-κB Signaling Compound Library

729 compounds
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9420 Exosome Compound Library

76 compounds
76 exosome-related compounds that can be used for high-throughput and high-content screening.

Libraries

FDA-Approved Kinase Inhibitor Library
L1610
Compounds: 263
NF-κB Signaling Compound Library
L3800
Compounds: 729
Exosome Compound Library
L9420
Compounds: 76
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